Conclusion

All three experiments combined to reveal the complete answer to the problem. MPF is made of two proteins that bind to make a complex. One is a hormone which codes for cdc28, which is a kinase. The regulatory subunit is a cyclin. People took cdc28 at 37 degrees C (dead cells) and gave yeast human DNA to try and discover a human homologue that would keep the cells alive at that temperature. Many human homologues were found as a result. They also discovered that a mutation in this complex was present in 90% of cancers. Thus, potential future research could include ways to create a loss of functional mutations in inhibitors and gain of cyclin-dependent kinases and cyclin. This is useful because it could eventually lead to a better understaning and possible cure for cancer.